Danomycin¹⁾, a product from a strain of Streptomyces albaduncus nov. sp., is a watersoluble antibiotic, orange red in color, and containing iron molecules in its polypeptide structure. Danomycin is effective in vitro against Gram-positive organisms such as Staphylococcus aureus and Pneumococccus, while ineffective against Staphylococcus albus, Streptococcus hemolyticus as well as Gram-negative bacteria.

Because of the high incidence of staphylococcal infections in infancy and young childhood, our concerns have been chiefly about danomycin with its clinical effect on staphylococcal infections. In vitro sensitivities of coagulase-positive staphylococci to danomycin and other several antibiotics, the blood levels and the urinary excretions of danomycin in children, and its clinical effects including the side effects have been studied.

The present report deals with our results obtained.