In the treatment of chronic sinusitis chemotherapeutic agents are widely used. However, in children, some kinds of therapeutic measure can be applicable only with difficulty. Furthermore, the problem of the strains which are resistant against penicillin and streptomycin and that of severe side effects of these chemicals frequently impede the application of chemotherapy.

The present author examined the therapeutic effect of broad spectrum antibiotics other than penicillin and streptomycin against chronic sinusitis in children. Only oral administration was used and no other local treatment was applied.

Though such general administration of antibiotics in the treatment of the disease in adults has been already reported by Ohsawa¹⁾, Peterson and Hadley²⁾and Arslan and De Vido³⁾, Menger⁴⁾, Lumin⁵⁾ and others, no report has been made on its application to children.