1957 Volume 10 Issue 5 Pages 205-212
A yellow crystalline antibiotic with weakly acidic properties has been isolated from the culture broth of a new species of Streptomyces. This organism, indexed S-66 in our culture collection, has been isolated from a soil sample collected from Aburabi, Shiga Prefecture. The antibiotic, which we have named aburamycin, is active against gram-positive organisms and, moreover, it shows some inhibitory effect on Ehrlich ascites tumor and Crocker sarcoma in mice.
The purpose of the presnt paper is to describe the antibiotic-producing organism and to report preliminary studies on production, isolation, antimicrobial spectrum, anti-tumor activities and properties of aburamycin.
