Nowadays the treatment of dermatomycosis, especially of tinea pedis, is considered to be falling into difficulties, although various kinds of medicament for fungous diseases appear every year, and it is universally agreed that the complete cure of tinea pedis is considerably unattainable even if a clinical healing is seen by treatment.

In this paper the clinical effect of variotin on dermatomycosis, including in vitro antifungal activity and animal experiment of the antibiotic was described.