This is a preliminary report on variotin in the treatment of skin diseases caused by Trichophyton. Variotin is an antifungal antibiotic discovered at the the Department of Antibiotics, the Institute for Applied Microbiology, Tokyo University, to be produced by Paecilomyces varioti var. antibioticus.

In our laboratory, the action on Trichophyton has been studied by Koide¹⁾ using an antibiotic prcduced by an Aspergillus since 1948. In this preliminary study on variotin, on account of small number of cases, a few cases diagnosed only by clinical symptoms were included, though mycolcgical diagnosis should be established.