Activity of Variotin, a New Antifungal Antibiotic

Shigemi Suzuki; Atsushi Suganuma; Tsunatarō Kishida; Akio Mizunoya; Fumiko Ueda; Yoshitaka Suzuki; Ichiro Kiji; Taiyō Kyo; Mannei Takeuchi; Shōzō Nakazawa; Norie Kishi; Sumie Tsumura

doi:10.11554/antibioticsa.12.5_244

Original articles

Activity of Variotin, a New Antifungal Antibiotic

Shigemi Suzuki, Atsushi Suganuma, Tsunatarō Kishida, Akio Mizunoya, Fumiko Ueda, Yoshitaka Suzuki, Ichiro Kiji, Taiyō Kyo, Mannei Takeuchi, Shōzō Nakazawa, Norie Kishi, Sumie Tsumura

Author information

Shigemi Suzuki
Department of Microbiology, Kyōto Prefectural Medical College
Atsushi Suganuma
Department of Microbiology, Kyōto Prefectural Medical College
Tsunatarō Kishida
Department of Microbiology, Kyōto Prefectural Medical College
Akio Mizunoya
Department of Microbiology, Kyōto Prefectural Medical College
Fumiko Ueda
Department of Microbiology, Kyōto Prefectural Medical College
Yoshitaka Suzuki
Department of Microbiology, Kyōto Prefectural Medical College
Ichiro Kiji
Department of Microbiology, Kyōto Prefectural Medical College
Taiyō Kyo
Department of Microbiology, Kyōto Prefectural Medical College
Mannei Takeuchi
Department of Microbiology, Kyōto Prefectural Medical College
Shōzō Nakazawa
Department of Microbiology, Kyoto Pharmaceutical College
Norie Kishi
Department of Microbiology, Kyoto Pharmaceutical College
Sumie Tsumura
Department of Microbiology, Kyoto Pharmaceutical College

JOURNAL FREE ACCESS

1959 Volume 12 Issue 5 Pages 244-248

DOI https://gongyi-jschina-com-cn-1416.res.gxlib.org.cn:443/rwt/1416/https/MSYXTLUQPJUB/10.11554/antibioticsa.12.5_244

Details

Abstract

Antifungal antibiotics so far existent have been all isolated frcm Streptomyces, while variotin is a substance produced by a fungus and, therefore, provides many specific characteristics. As ever as the discovery of new antibiotics, variotin was investigated for antibacterial spectrum against organisms and fungi and for influence on respiration of protozoa and tumor cells. Besides, were studied emergence and speed of variotin resistance as well as antagonistic substance to variotin.

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