1963 Volume 16 Issue 4 Pages 155-156
Antiprotozoal activities were reported on some antibacterial and antifungal antibiotics with strong toxicity. The antibiotic substances which inhibit or destroy protozoa are presumed to have general cytotoxicity. Antibiotics having a very broad spectrum, e.g. substances active against bacteria and protozoa can be expected to be more toxic than antibiotics with a specific activity only against protozoa. This presumption indicates the importance of including an antiprotozoal test already into the primary screening course. This paper reports the screening method which has been used in the authors laboratory.