The Journal of Antibiotics, Series A
Online ISSN : 2435-5135
Print ISSN : 0368-1173
ISSN-L : 0368-1173
Original articles
Studies on Streptomycetes Simultaneous Production of Oleandomycin and Chromomycins by Streptomyces Olivochromogenes No. 69895
Eiji HigashideToru HasegawaMotoo ShibataKomei MizunoMasahiko ImanishiAkira Miyake
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1965 Volume 18 Issue 1 Pages 26-37

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Abstract

A strain, Streptomyces sp. No. 69895, was isolated from a soil sample collected in Sikkim. The present authors found that strain produced two antibiotics, antibiotic 69895 A and B, simultaneously and identified them to be chromomycin1,2,3,4) and oleandomycin5), respectively. Up to now, St. griseus No. 71) was reported as a chromomycins-producing strain and St. antibioticus ATCC 118916) as an oleandomycin-producing strain. On theother hand, many streptomyces strains producing antibiotics related to chromomycin or oleandomycin were reported. But the above-mentioned strain was found to differ from those producing chromomycin, oleandomycin or antibiotic related to them only, and a streptomyces strain which produce chromomycin and oleandomycin simultaneously has never reported.

The present paper deals with the mycological properties of Streptomyces sp. No. 69895, comparison of the properties of the strain with those of related streptomyces strains, extraction and purification procedure, and physicochemical properties of antibiotics 69895 A and B.

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© 1965 JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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