1965 Volume 18 Issue 1 Pages 38-42
Two new polyhydroxy basic antibiotics have been isolated from a culture broth of a Streptomyces obtained from a soil sample collected in Yokohama, Japan, the major component named destomycin A and the minor one named destomycin B. The organism was characterized to form the aerial hyphae with secondary whorls and was assigned to a new species, Streptomyces rimofaciens by T. Niida in our laboratory.
Destomycins A and B are broad antimicrobial epectrum antibiotics, especially active against some kinds of fungi. Destomycin A is more active against Mycobacteria than destomycin B.
In the present publication, the production, isolation and characterization of destomycins are described.
