Studies on Pyrrolnitrin, a New Antibiotic. I Isolation and Properties of Pyrrolnitrin

Kei Arima; Hiroshi Imanaka; Masanobu Kousaka; Akio Fukuda; Gakuzo Tamura

doi:10.11554/antibioticsa.18.5_201

Original Articles

Studies on Pyrrolnitrin, a New Antibiotic. I Isolation and Properties of Pyrrolnitrin

Kei Arima, Hiroshi Imanaka, Masanobu Kousaka, Akio Fukuda, Gakuzo Tamura

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JOURNAL FREE ACCESS

1965 Volume 18 Issue 5 Pages 201-204

DOI https://gongyi-jschina-com-cn-1416.res.gxlib.org.cn:443/rwt/1416/https/MSYXTLUQPJUB/10.11554/antibioticsa.18.5_201

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Abstract

In the course of screening of antibiotics, a new antibiotic was obtained from the cells of a bacterium which was isolated from a soil sample collected in Chiba Prefecture, Japan.

The cultural characteristic of the bacterium was investigated by the authors¹⁾. The antibiotic was named pyrrolnitrin and isolated as pale yellow crystals. Pyrrolnitrin has a growth inhibitory effect against fungi, yeasts and Gram-positive bacteria, and has low toxicity.

This paper deals with fermentation, isolation and properties of pyrrolnitrin.

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