The Journal of Antibiotics, Series A
Online ISSN : 2435-5135
Print ISSN : 0368-1173
ISSN-L : 0368-1173
Original Articles
Cytological Study on the Effect of Neocarzinostatin on Sarcoma 180 in vivo
Taisuke NishikawaKatsuo KumagaiAkira KudoNakao Ishida
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1965 Volume 18 Issue 5 Pages 223-227

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Abstract

Neocarzinostatin is a new antibiotic isolated from culture filtrate of Streptomyces carzinostaticus F-411). The antibiotic exerts a striking inhibitory effect on growth of some experimental tumors1) and various studies have been made in this laboratory to elucidate the mode of action of neocarzinostatin2,3). The present report concerns with the cytological changes of sarcoma 180 tumor cells produced by neocarzinostatin in vivo.

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© 1965 JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
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