Annals of the Japanese Respiratory Society
Online ISSN : 2186-5884
Print ISSN : 2186-5876
ISSN-L : 2186-5876
Case Reports
A case of disseminated nocardiosis caused by Nocardia pseudobrasiliensis
Shohei Gaja Morikazu AkamineSeishiro ArimaYui NahaTeruhito UchiharaKazuko Yamamoto
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2025 Volume 14 Issue 3 Pages 131-135

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Abstract

Pulmonary nocardiosis is a rare opportunistic infection primarily affecting immunocompromised individuals, characterized by the potential for disseminated lesions throughout various organ systems. In the current case, Nocardia pseudobrasiliensis was isolated from a pleural fluid culture, with a concomitant brain abscess identified as a disseminated manifestation of the disease. The patient underwent a comprehensive treatment regimen comprising ciprofloxacin and additional antimicrobial agents for a duration of 12 months, resulting in the successful resolution of all identified lesions. Notably, Nocardia pseudobrasiliensis exhibits a propensity for resistance to sulfamethoxazole-trimethoprim; thus, precise bacterial identification and antimicrobial susceptibility testing are imperative for effective management of this infection.

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© 2025 The Japanese Respiratory Society
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