2025 Volume 14 Issue 3 Pages 131-135
Pulmonary nocardiosis is a rare opportunistic infection primarily affecting immunocompromised individuals, characterized by the potential for disseminated lesions throughout various organ systems. In the current case, Nocardia pseudobrasiliensis was isolated from a pleural fluid culture, with a concomitant brain abscess identified as a disseminated manifestation of the disease. The patient underwent a comprehensive treatment regimen comprising ciprofloxacin and additional antimicrobial agents for a duration of 12 months, resulting in the successful resolution of all identified lesions. Notably, Nocardia pseudobrasiliensis exhibits a propensity for resistance to sulfamethoxazole-trimethoprim; thus, precise bacterial identification and antimicrobial susceptibility testing are imperative for effective management of this infection.